Dissecting statistical genomics and psychiatric epidemiology...
Curriculum Vitae
LAST UPDATED
November 3, 2024
NAME
Franjo Ivankovic
OFFICE ADDRESS
185 Cambridge St, CPZN-6823A, Boston, MA 02114
MAILING ADDRESS
160 Alewife-Brook Pkwy #1287, Cambridge, MA 02138
EMAIL ADDRESS
info@franjo.us (business/personal)
fivankovic@broadinstitute.org (academic, preferred)
fivankovic@mgh.harvard.edu (academic, nonpreferred)
SIGNATURE
Education
05/2017
B.S.
Integrative Biology
University of Florida
Gainesville, FL
05/2017
B.A.
Anthropology
University of Florida
Gainesville, FL
08/2022
Ph.D.
Genetics and Genomics
Advisor: Carol Mathews, MD
Dissertation: Genomics and Phenomics of OCD and Related Disorders
University of Florida
Gainesville, FL
Postdoctoral Training
08/2022 – Present
Research Fellow
Analytic and Translational Genetics Unit
Advisor: Benjamin Neale, Ph.D.
Massachusetts General Hospital,
Boston, MA
Appointments at Hospitals and Affiliated Institutions
08/2022 – Present
Affiliate Postdoc
Stanley Center for Psychiatric Research
Program in Medical and Population Genetics
Advisor: Benjamin Neale, Ph.D.
Broad Institute of MIT and Harvard
Cambridge, MA
08/2022 – Present
Affiliate Postdoc
Department of Medicine
Advisor: Benjamin Neale, Ph.D.
Harvard Medical School
Cambridge, MA
08/2022 – Present
Visiting Researcher
Institute for Molecular Medicine
Advisor: Mark Daly, Ph.D.
University of Helsinki
Helsinki, Finland
Other Professional Positions
2010 – Present
eSTEMM, LLC
President, consultant, tutor.
4 hours per week
Committee Service
Local
2018 – 2022
Admissions and Conference Organizing Committee
Genetics Institute,
University of Florida
.
2018 – 2022
Member/Assistant
2021 – 2022
Seminar Committee
Center for OCD, Anxiety, and Related Disorders,
University of Florida
.
2021 – 2022
Member
2023
Broad Summer Scholars Program Pre-Selection Committee
Broad Institute of MIT and Harvard
.
2023
Member
2023 – Present
Program Meeting Committee
Stanley Center for Psychiatric Research,
Broad Institute of MIT and Harvard
.
2023 – 2024
Member
2023 – Present
Institutional Review Board
Massachusetts General Brigham
.
2023 – 2024
Member
Professional Societies
2015 – 2024
American Association for Advancement of Science
2015 – Present
The American Society of Human Genetics
.
2016 – 2024
DNA Day Essay Contest Judge
.
2024
Abstract Reviewer: Complex Traits and Polygenic Disorders
2020 – Present
International Society of Psychiatric Genetics
2022 – 2024
American Psychological Association
2023 – Present
European Society of Human Genetics
2023 – Present
Society for Epidemiologic Research
.
2024
Abstract Reviewer
Editorial Activities
Ad hoc Reviewer
- Cell Press STAR Protocols
- Journal of Open-Source Software
- Journal of the American Academy of Child and Adolescent Psychiatry
- Psychiatric Genetics
Honors and Prizes
2011
Erste Stiftung Scholarship
Erste Bank and Foundation
Scholarship
2013
United World College Scholarship
University of Florida Honors Program
Scholarship
2015
Davis United World College Block Tuition Award
University of Florida Honors Program
Scholarship
2017
Graduate School Fellowship
University of Florida Genetics Institute
Training
2017
Genetics Institute Award
University of Florida Genetics Institute
Training
2017
Travel Award
University of Florida Genetics Institute
Travel
2020
NINDS Movement Disorders and Neurorestoration T32
National Institute of Neurological Disorders and Stroke; University of Florida College of Public Health and Health Professions
Training
2020
ErstSummer Institute in Statistical Genetics Scholarship
University of Washington Department of Biostatistics
Training
2020
Trainee Enhancement Opportunity Award
University of Florida McKnight Brain Institute
Training
2020
Travel Award
University of Florida Genetics Institute
Travel
2021
Travel Award
University of Florida Genetics Institute
Travel
2022
Toffler Research Award
University of Florida McKnight Brain Institute
Training
2022
Graduate School Mentoring Award
University of Florida Graduate School
Scholarship
2022
Travel Award
University of Florida Genetics Institute
Travel
2022
Eliana Hechter Travel Fellowship
Broad Institute of MIT and Harvard
Travel
Report of Local Teaching and Training
Teaching of Students in Courses
2016
PCB3063: Genetics
University of Florida, Gainesville, FL
.
Undergraduate students
3 hours per week, 29 weeks
Research Supervisory and Training Responsibilities
2018 – 2022
Supervision and teaching of undergraduate and graduate students
University of Florida, Gainesville, FL
.
Average 1-2 students a year.
1:1 supervision and teaching activities, about 5 hours per week per student.
2022 – Present
Statistical training of peers
Massachusetts General Hospital, Boston, MA
.
Average 2-3 peers a year.
1:1 teaching activities, about 2 hours per week per peer.
2022 – Present
Supervision and teaching of undergraduate students
Broad Institute of MIT and Harvard, MA
.
Average 1 student a year.
1:1 supervision and teaching activities, about 2 hours per week per student.
Formally Mentored Harvard Students
2023
Emily Gao, Harvard College Class of 2026
.
Career stage: undergraduate student; Mentoring role: research mentor.
Other Mentored Trainees and Faculty
2018 – 2019
Kata Alilovic, B.S. / Bioengineering and Biomedical Engineering Ph.D. Student, Cornell University in Ithaca, NY
.
Career stage: undergraduate student; Mentoring role: research mentor.
2018 – 2019
Lt Col Emily Marr, M.S. / Biology Instructor, United States Air Force Academy in Colorado Springs, CO
.
Career stage: masters student, Mentoring role: research mentor.
2018 – 2020
Mayank Kotadia, B.S. / Medical Student, University of Florida College of Medicine in Gainesville, FL
.
Career stage: masters student, Mentoring role: research mentor.
2021 – 2023
Sharon Johnson, B.S. / Research Associate, Greenlight Biosciences in Medford MA
.
Career stage: undergraduate student, Mentoring role: research mentor, Accomplishments: two co-author papers in preparation.
2021 – 2023
James Shen / Undergraduate Student, University of Florida College of Engineering in Gainesville, FL
.
Career stage: undergraduate student, Mentoring role: research mentor, Accomplishments: two co-author papers in preparation.
2021 – 2024
Daisy Valle, B.S. / Medical Student, University of Florida College of Medicine in Gainesville, FL
.
Career stage: undergraduate and medical student, Mentoring role: research mentor, Accomplishments: first author-paper in preparation.
Local Invited Presentations
No presentations below were sponsored by third parties/outside entities.
2017
CRISPR/Cas9 Knock-Ins of Expanded CTG DNA Repeats / Seminar
.
University of Florida Genetics and Genomics Seminar
2018
Detecting CUG Repeats with CRISPR/Cas13a / Seminar
.
University of Florida Center for Neurogenetics
2018
RNA Repeat Expansion Detection with CRISPR/Cas13a / Seminar
.
University of Florida Genetics and Genomics Seminar
2019
CRISPR/Cas9 Knock-In Mouse Model of Myotonic Dystrophy Type 1 / Seminar
.
University of Florida Center for Neurogenetics
2019
Repetitive Elements in Disease / Seminar
.
University of Florida Genetics and Genomics Seminar
2020
Introduction to Psychiatric Genetics / Seminar
.
University of Florida Genetics and Genomics Seminar
2020
Statistical Genetics: Approaches to Tourette Syndrome and Obsessive-Compulsive Disorder / Seminar
.
University of Florida Center for OCD, Anxiety, and Related Disorders
2020
Genetic Underpinnings of Tourette Syndrome: A Genome-Wide Analysis of Copy-Number Variation / Joint T32 and Movement Fellows Research Symposium
.
University of Florida Norman Fixel Institute for Neurological Disorders
2020
Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome? / Seminar
.
University of Florida Center for OCD, Anxiety, and Related Disorders
2021
Copy-Number Variants in Tourette Syndrome / Student Showcase
.
University of Florida Genetics Institute
2021
Genetic Aspects of Obsessive-Compulsive and Tic Disorders / Joint T32 and Movement Fellows Research Symposium
.
University of Florida Norman Fixel Institute for Neurological Disorders
2022
Epidemiology and Genome-Wide Association Study of Obsessive-Compulsive Disorder in the Adolescent Brain Cognitive Development Study / Seminar
.
University of Florida Center for OCD, Anxiety, and Related Disorders
2022
Epidemiology and Genome-Wide Association Study of Obsessive-Compulsive Disorder in the Adolescent Brain Cognitive Development Study / Seminar
.
University of Florida Genetics and Genomics Seminar
2022
Optimization of Psychiatric Phenotypes for Genetic Analyses in the Adolescent Brain Cognitive Development Study / Seminar
.
University of Florida Center for OCD, Anxiety, and Related Disorders
Report of Education of Patients and Service to the Community
No presentations below were sponsored by third parties/outside entities.
Activities
2016 – 2018
University of Florida Genetics Club / Founder and President
.
Formed the club, organized annual community-engaging DNA Day celebrations in partnership with the UF Genetics Institute.
2015 – 2020
University of Florida Health StreetLight / Volunteer and Team Captain
.
Volunteered and led a team of volunteers at UF Health’s Children Hospital.
2017 – 2022
Alachua County School District / Science Fair Judge
.
Served as a science fair judge at local and regional science fairs.
2021 – 2022
Scientist in Every Florida School / Visiting Speaker
.
Gave educational talks to high-school students across the State of Florida.
2023 – Present
Massachusetts Science + Engineering Fair
.
Served as a science fair judge at local and regional science fairs. Served on the Judge Advisory Group in 2024.
Educational Material for Patients and the Lay Community
Books, articles, and presentations in other media
2021
Bringing student-driven genetics education to the university campus
Author
Article, PLOS Blogs [LINK]
Report of Scholarship
ORCID: 0000-0002-6776-8626
Peer Reviewed Scholarship in Print or Other Media
Research Investigations
- Li J, Tseng CS, Federico A, Ivankovic F, Huang YS, Ciccodicola A, Swanson MS, and Yu P. SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets. Database. 2017 Sep;2017. [PMID 29220461; DOI: 10.1093/database/bax071] [DOWNLOAD PDF]
- Li J, Deng SP, Vieira J, Thomas J, Costa V, Tseng CS, Ivankovic F, Ciccodicola A, and Yu P. RBPMetaDB: a comprehensive annotation of mouse RNA-Seq datasets with perturbations of RNA-binding proteins. Database. 2018 Jun;2018. [PMID: 29931156; DOI: 10.1093/database/bay054] [DOWNLOAD PDF]
- Nutter CA, Bubenik JL, Oliveira R, Ivankovic F, Sznajder ŁJ, Kidd BM, Pinto BS, Otero BA, Carter HA, Vitriol EA, Wang ET, and Swanson MS. Cell-type-specific dysregulation of RNA alternative splicing in short tandem repeat mouse knockin models of myotonic dystrophy. Genes Dev. 2019 Dec;33(23-24):1635-1640. [PMID: 31624084; DOI: 10.1101/gad.328963.119] [DOWNLOAD PDF]
- Sznajder ŁJ, Scotti MM, Shin J, Taylor K, Ivankovic F, Nutter CA, Aslam FN, Subramony SH, Ranum LPW, and Swanson MS. Loss of MBNL1 induces RNA missprocessing in the thymus and peripheral blood. Nat Commun. 2020 Apr;11:2022. [PMID: 32332745; DOI 10.1038/s41467-020-15962-x] [DOWNLOAD PDF]
- Claudio-Campos K, Stevens D, Koo SW, Valko A, Bienvenu J, Budman CA, Cath DC, Darrow S, Geller D, Goes FS, Grados MA, Greenberg BD, Greenberg E, Hirschtritt ME, Illman C, Ivankovic F, King RA, Knowles JA, Krasnow J, Lee PC, Lyon GJ, McCracken JT, Robertson MM, Osiecki L, Riddle, MA, Rouleau G, Sandor P, Nestadt G, Samuels J, Scharf JM, and Mathews CA. Is persistent motor or vocal tic disorder a milder form of tourette syndrome? Mov Disord. 2021 Aug;36(8)1899-1910. [PMID: 33942911; DOI: 10.1002/mds.28593] [DOWNLOAD PDF]
- Ivankovic, F, Johnson, S, Shen, J, Scharf, JM, and Mathews CA. Optimization of self‐ or parent‐reported psychiatric phenotypes in longitudinal studies. J Child Psychol Psychiatry. 2021 Sep. [PMID: 39246252; DOI: 10.1111/jcpp.14054] [ONLINE FULL TEXT]
Scholarship without Named Authorship
- Jain P, Miller-Fleming T, Topaloudi A, Yu D, Drineas P, Georgitsi M, Yang Z, Rizzo R, Müller-Vahl KR, Tumer Z, Mol Debes N, Hartmann A, Depienne C, Worbe Y, Mir P, Cath DC, Boomsma DI, Roessner V, Wolanczyk T, Janik P, Szejko N, Zekanowski C, Barta C, Nemoda Z, Tarnok Z, Buxbaum JD, Grice D, Glennon J, Stefansson H, Hengerer B, Benaroya-Milshtein N, Cardona F, Hedderly T, Heyman I, Huyser C, Morer A, Mueller N, Munchau A, Plessen KJ, Porcelli C, Walitza S, Schrag A, Martino D; Psychiatric Genomics Consortium Tourette Syndrome Working Group (PGC-TS)*; EMTICS collaborative group; Dietrich A; TS-EUROTRAIN Network; Mathews CA, Scharf JM, Hoekstra PJ, Davis LK, Paschou P. Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome. Transl Psychiatry. 2023; Jun; 12(1):69. [PMID: 36823209, DOI: 10.1038/s41398-023-02341-5] [DOWNLOAD PDF] (*member of the writing group cited in the appendix of the manuscript)
Thesis
- Ivankovic F. Genomics and Phenomics of OCD and Related Disorders [dissertation]. [Gainesville (FL)]: University of Florida ProQuest Dissertations Publishing, 2022. 29320020. 245p. [DOWNLOAD PDF]
Manuscripts Submitted to Preprint Servers
- Liao C, Ye R, Ivankovic F, Fu JM, Walters R, Lowther C, Walkanas E, Churchhouse C, Samocha KE, Lindblad-Toh K, Karlsson E, Hiller M, Talkowski ME, Neale BM. The landscape of gene loss and missense variation across the mammalian tree informs on gene essentiality. bioRxiv. 2024. [DOI: 10.1101/2024.05.16.594531] [DOWNLOAD PDF]
- Ramirez-Diaz AM, Diaz-Zuluaga AM, Stroud RE, II, Vreeker A, Bitta M, Ivankovic, F, Wootton O, Whiteman CA, Mountcastle H, Jha SC, Georgakopoulos P, Kaur I, Mena L, Asaaf S, de Souza Rodrigues AL, Ziebold C, Newton CRJC, Stein DJ, Akena D, Valencia-Echeverry J, Kyebuzibwa J, Palacio-Ortiz JD, McMahon J, Ongeri L, Chibnik LB, Quarantini LC, Atwoli L, Santoro ML, Baker M, Diniz MJA, Castaño-Ramirez M, Alemayehu M, Holanda N, Ayola-Serrano NC, Lorencetti PG, Mwema RM, James R, Albuquerque S, Sharma S, Chapman SB, Belangero SI, Teferra S, Gichuru S, Service KS, Kariuki SM, Freitas TH, Zingela Z, Gadelha A, Bearden CE, Ophoff RA, Neale, BM, Martin AR, Koenen KC, Pato CN, Lopez-Jaramillo C, Reus V, Freimer N, Pato MT, Gelaye B, Olde Loohuis L. Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project). medRxiv. 2024. [DOI: 10.1101/2024.10.02.24314732] [DOWNLOAD PDF]
Abstracts, Poster Presentations, and Exhibits Presented at Professional Meetings
- Genetics of Childhood Psychiatric Burden and Obsessive-Compulsive Disorder. World Congress of Psychiatric Genetics 2021. Virtual.
- Genetics of Childhood Psychiatric Burden and Obsessive-Compulsive Disorder. 5th Annual Diversity Graduate Research Symposium of University of Florida Black Graduate Student Organization and the Society for Advancing Chicanos and Native Americans in Science 2021. Gainesville, FL.
- Rare Copy-Number Variants in Tourette Syndrome. 2022 University of Florida College of Medicine Research Day. Gainesville, FL.
- Genomics and Phenomics of Obsessive-Compulsive and Related Phenotypes in Adolescent Brain Cognitive Development Study. 2022 University of Florida College of Medicine Research Day. Gainesville, FL.
- Rare Copy-Number Variants in Tourette Syndrome and Related Disorders. 2022 Annual Meeting of the Society of Biological Psychiatry. New Orleans, Louisiana.
- Genomics and Phenomics of Obsessive-Compulsive and Related Phenotypes in Adolescent Brain Cognitive Development Study. 2022 Annual Meeting of the Society of Biological Psychiatry. New Orleans, Louisiana.
- Genetic and Phenotypic Architecture of OCD in ABCD Study. World Congress of Psychiatric Genetics 2022. Florence, Italy.
- Copy-Number Variation in Tourette Syndrome Families, Analysis of de novo and Inherited CNVs. World Congress of Psychiatric Genetics 2022. Florence, Italy.
- Leveraging Multi-Modal Data from the ABCD Study to Refine OCD Phenotype for Genetic Analyses. World Congress of Psychiatric Genetics 2022. Florence, Italy.
- Optimization of Psychiatric Phenotypes for Genetic Studies. 2023 Annual Meeting of the Society of Biological Psychiatry. San Diego, California.
- Uncovering Genetics of Anorexia and Bulimia Nervosa Through Large Scale Sequencing. Eating Disorders Research Society 2023. Boston, Massachusetts.
- Marker Match: A Proximity Based Probe-Matching Algorithm for Joint Analysis of CNVs From Different Genotyping Arrays and Subsequent CNV Association Study of Tourette Syndrome. World Congress of Psychiatric Genetics 2023. Montreal, Canada.
- Genome-Wide Analyses of Inattention and Hyperactivity/Impulsivity: Biological and Clinical Implications for Attention Deficit Hyperactivity Disorder. World Congress of Psychiatric Genetics 2023. Montreal, Canada.
- Uncovering Genetics of Anorexia and Bulimia Nervosa Through Large Scale Sequencing. Molecular Psychiatry Association 2024. Kailua-Kona, Hawai’i.
- Uncovering Genetics of Anorexia and Bulimia Nervosa Through Large Scale Sequencing. Molecular Psychiatry Association 2024. Singapore, Singapore.
